I have actually done this for all my grandfathers siblings when I was trying to find out what happened to him after he disappeared in 1908. I didn't find it very difficult. The surname was Johns which is a very common name and I was going back to the 1870's. This is how I went about it-
First I looked on Free BMD to trace their marriages and where neccesary I ordered certificates. Then I used the same website to trace any children by using the surname and then adding the mothers surname. From there I traced their deaths and ordered the death certificates, I did this as many times as was needed to bring me up to the present day and to find an informants name. I then looked for the informants names and addresses using telephone websites.I wrote to them all also adding my email address.
Without exception I received a reply and I had found the right descendants. There was only one problem, one had disappeared but at least the person who bought his house replied to let me know.
Incidentally, I still didn't find out what happened to my grandfather.
I hope this has been of some help and you are able to follow my explanation.
Good Luck and I hope it works for you.