Edward Kelly (Ned), my great, great, great grandfather, was born in 1771 in Portarlington Queens County. As far as I know and all my research shows, he had no brothers. He had five daughter and one son who lived to be adults. His son, also Edward Kelly, died in India without issue in early 1828. His father died in India later in the same year. In 1818-1819 he was in Ireland with his wife and family.
I don't think that you are related to us as Ned's father and his father's brother and their children are all known. Whether you are descended from a brother of Thomas Kelly (Ned's grandfather) is another matter and none of us who are doing research on the family have been able to find anything about his parents or his wife.