James Alexander Knowles, Sr is my 6th great-grandfather also. I have been unable to confirm any information past James, except for generic information about the Samuel, Robert, Robert, Damon, Damon connection.
Are you from James' line with Patience Darville (like me) or Hannah Campbell? My family line is listed in the Bahamas DNA project, and James is the farthest back they have also. We are still searching though.