Hi Pat
I am also a Ruffner descended from Simon and Barbara. Was looking through my info and I found an Anna Margaret Ruffner born 11/18/1777 to Simon Ruffner and Catherine Griffin. She married a John Edward Smythe. Not much help but that is all I could find. Have you checked the Goshenhoppen Registers. They are quite helpful as to the listing of many births of Ruffners.
Pat