Thanks Mary, that clears it up a little. I did the same, only learning later my mistake after they had came over to the USA and suddenly Josefa became Josephine after I found it in the US census! Learned to look a lot closer for gender indications after that.
Guess I was looking for an easy "mark" to try to distinguish them. Think I finally got it though, as I'm fairly certain now I'm dealing with father/son and that son remarried. I'm still searching for the marriage to confirm, but I found the death of the 1st wife so I'm fairly certain this is what happened.
Just made me a little crazy to see 3 sets of Mikulas with 3 wives all named either Marie Anna or Marianne. Not nearly as good at languages to pick up on that. Thanks for helping me out.