It is a pity you did not put more detail in your message. I have a Van Horne family in my family tree in Kent Co. They are descendants of Dan Van Horne, who married Annie Irene Vosburgh 13 Mar 1882.
A son, Albert Ernest(1882-1981) married Maude Williston in Dec 1903; The next generation Earle (1904-1964) married Mary E Smith 31 Mar 1928.

I have not pursued the ancestors of Dan Van Horne because he is the spouse of a cousin: Annie Vosburgh is my wife's 2nd cousin 2 generations removed and by curious coincidence, Maude Williston is my 3rd cousin 3 generations removed.

Yours M.Keith Abel