Did Amelia have children? If she did, names and dates and places of birth would help in a search for her.
The age is off, but is this a possibility?
1860 CA San Francisco, 10th District June 5
[lodging house]
Amelia LITTLETON, age 23, female, seamstress, born England
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1870 CA San Francisco, 8th Ward
LITTLETON, Amelia, age 30, female, white, keeping house, value of Real Estate: 4000, personal property: 600, born England.