I looked again and could not find a John or Amos Hand. There are, however, several Mary McQuoids in the Union Co IN area at different times than the 1809 that you offered that I have no husband listed for. Are you sure about the year?
1809 is really early for Indiana and the McQuoids were probably few, and relatively new to the area from NJ at this point.
My email address is listed, it may be more efficient way of communicating.