Gloria,
Witha a little eavesdropping and a little digging I came up with the info that you seek. All of the following info came from the book, "Early Families of Eastern and Southeastern Ky." by Kozee. Your local library should have a copy. At least mine does.
This is a place or local name, "of Preston". The family is English and there are no less than 24 parishes situated in every part of England which bear the name. The Hundred Rolls of 1273 bear the names Laurence de Preston, Linconshire county; Alice de Preston, Northampton county; Adam de Prestone, Salop county; John de Prestone of Preston, Somerset county. The tax lists of 1379 bear the names Isabella de Preston and Johnanna de Pryston of County Yorks.
The family of Preston was numerous in all the original thirteen colonies.
Reputable historians and writers have stated that the early progenitors of the Prestons of the Big Sandy Valley, in Eastern Kentucky, were Francis Preston, Charles Preston, William Calvert Preston and Robert Preston, all of whom emigrated from England and settled in Maryland.
Moses Preston and Nathan Preston, brothers, and Revolutionary War soldiers, and their sister, Mrs. Elizabeth (Preston) Burgess, were the first of the family of Preston to emigrate and settle in the Big Sandy Valley, Eastern Kentucky, in the Great Western Movement. These brothers were the progenitors of a relatively large number--if not all--of the Prestons of Eastern Kentucky. They emigrated from Bedford county, Virginia, and settled in Floyd county about 1800.
Nathan Preston was b., presumably in Bedford county, Virginia, in 1761. (Then it tells his service record and which battles he participated in). Soon after his discharge from the service, he returned to his home in Bedford county and in August, 1780, in that county, he m. Elizabeth Vaughan, b. about 1760, "by publication three times at church by the Rev. Mr. Ramsay".
It appears from an affidavit executed by Jeffrey Preston, a son, that eight children were b. to Nathan Preston and Elizabeth. However, only six children were mentioned in said affidavit, as follows:
1. Nancy Preston; m. Benjamin Hylton
2. Edy Preston; m. francis Ashbury Brown

3. Jeffrey Preston, farmer; b. in Bedford county, Virginia, about 1792; m. in Floyd County, Kentucky, about 1814, Jane (Jincy) Burgess, b. in Va. in 1796, daughter of Garland Burgess. Children: Burgess, Col. Nathan Preston Jr., Eliphus Preston, Jr., Mrs. Henry Sherman, Mrs. William Randoph, Mrs. Mace Mahan, and Mrs. John H. Ward.

4. Mitilda Preston; b. in Bedord county, Va.; m. in Floyd Co. Ky, Dec. 23, 1819, Bracken Lewis

5. Eliphus Preston, farmer; b. in Bedford county, Va. about 1795; m., in Floyd county, Ky, December 10, 1815, Annie Pelphrey, daughter of John Pelphrey. The records would seem to indicate that children of Eliphus Preston and Annie were among others; Atchison Preston; b. in 1825, Harrison Preston; b. in 1835, and Leah J. Preston; b. in 1839.
The United States Census, Johnson county, 1860, shows that the were then living in the household of Jeffrey Preston, (misprint, should be Eliphus Preston, I checked against names in 1850), the following: Lucinda Preston--apparently second wife, b. in Ky. in 1827--and their children: Thomas Jefferson Preston; b. in 1847, Julia A. Preston; b. in 1848, Mary J. Preston; b. in 1849, Matilda Preston; b. in 1851, Cynthia A. Preston; b. in 1853, James L Preston; b. in 1857, and Isaac L. Preston; b. in 1859.

6. Elizabeth Preston b. Bedford county, Va., m., in Floyd county, Ky., September 25, 1811, James VanHoose, Sr.,

There is much more to this chapter than I can possibly put on this page. I am sure it would be worth your while to visit somewhere you could view the chapter!
Hope you enjoy!
Chris Cheek Fry