Jim,
I have little more on this line than what I posted here. I think JPDownard has more information and better documentation than I do. These names are at the furthest back I have associated with my line, and much of the earlier 2-3 generations is totally unsubstantiated. The following is what I have on Ignatious and Sarah:
Descendants of Ignatious Howard

1 Ignatious HOWARD b: 1725 in St. Mary's City, St. Mary's Co., MD d: 1777 in Greenbrier Co., VA
.. +Sarah SIMS b: 20 Sep 1726 in St. Peter's Parish, New Kent Co., VA m: Abt. 1745 in Greenbrier Co., VA d: 04 Apr 1789 in Greenbrier Co., VA
... 2 Thomas HOWARD b: 08 Jun 1750 in Wilkes Co., GA d: 26 Jan 1853 in Morgan Co., KY
....... +Frances /?/ m: 1794 in Washington Co., VA
... 2 James HOWARD b: 1752 in Wilkes Co., GA d: 1790-1792 in Madison Co., KY
....... +Hannah GEFFERS b: Abt. 1755 m: 23 Aug 1780 in Rockingham, Greenbrier Co., VA d: 30 May 1837 in Madison Co., KY
... 2 Elizabeth HOWARD b: 1755 in Agusta Co., VA d: Aft. 1831 in Miami Co., OH
....... +Abraham FRIEND b: 1754 in Agusta Co., VA m: 1775 in Greenbrier Co., VA d: 1829 in Miami Co., OH or Rush Co., IN
... 2 John HOWARD b: Abt. 1757
... 2 Benjamin HOWARD b: Abt. 1760
... 2 Henry HOWARD b: 02 Oct 1763 d: 17 Mar 1798 in Clark Co., KY
....... +Isabella GRIFFIN b: 1762 in VA m: Oct 1777 in Greenbrier Co., VA d: 25 Jun 1850 in Powell Co., KY
... 2 Anna HOWARD b: 1770 in Montgomery Co., VA d: Aft. 1840 in Randolph, MO
....... +Nimrod TACKETT b: Abt. 1765 in VA m: 15 Mar 1787 in Greenbrier Co., VA d: 1837 in MO
... 2 Charles HOWARD b: Abt. 1771
... 2 Samuel HOWARD b: Abt. 1772
... 2 Mary HOWARD b: Abt. 1773 in VA
....... +James RIGGENS m: 1791 in Washington Co., VA
There are some pretty unlikely dates/places in here. Do not consider this more than a research guide. That is what it is to me, and I haven't been working on this line for a couple of years.
e-mail me at PVHoward@pcez.com to exchange more details and stay in touch.
Paul in Oregon