Thank you Dorris for some additional detail. I found these links that are helpful:
Boone's Lick State Historic Site
http://mostateparks.com/park/boones-lick-state-historic-siteArrow Rock
http://en.wikipedia.org/wiki/Arrow_Rock,_MissouriAre there extant hotels from the 1880s in Warren County or St. Charles County?
Thanks again for the leads,
Tom