My fifth great grandfather's name was James W. Owen and he was born right around 1808. You said he was in Missouri and Tennessee, but that you can't find any other info and that the woman he was married to may have been his second wife. I remember my great grandmother telling me that his first wife died early on and that supposedly he left the rest of the family and did not return. I am from Kentucky (also where he started my branch of the family tree). I'm interested to see if they are the same James Owen and if maybe he started a new life in a new state. Because this was so long ago, it was common for men to change their history including birthplace. Let me know if you'd like to discuss further.