Holland Guthrie McDaniel b about 1800 (She was 50 on the 1850 Onslow Co census) was my mother's great-great-grandmother through Holland's son William Thomas Guthrie & Polsey King. In Records of Onslow Co., page 1432, I found the following information:
Edward McDaniel & wife Roseland appointed guardians to Isaac McDaniel June 5, 1849.
I suspect Daniel McDaniel had died. Edward & Roseland were married 7 Feb. 1848 and Edward was possibly the son of Daniel by his first wife.