My dad is from Bryson City (we all live in Michigan now) and I'm researching the same surnames you listed!
-- My grandmother was Sarah Lucinda Lula Belle BARKER that married Roy JENKINS.
-- Lula's mother was Mary FRADY, the daughter of William & Sally (COX) FRADY
-- Her father was William Grant BARKER--the out-of-wedlock son of Edith Ellege BROOKS and Warren BARKER; & he had a sister named Mary Magdalene BARKER.
-- Edith first had two children by her husband Humphrey P. BROOKS--Zebulon Vance BROOKS & Emmiline BROOKS (married FRADY
-- Also my first cousin Evelyn JENKINS married Matthew BROOKS
-- And my maiden name was JENKINS
I'd love to compare our connections.