In case you don't have it, Wes Cochran's transcription in Belmont Co., OH Marriages, 1803-1849 is:
George Mayhue & Matilda Spencer 27 Nov 1828.
Also more info. in Genealogical Records in Belmont Co., OH, Vol. 6, pg. 29:
George Mayhue and Matilda Spencer both of Somerset Twp. on 27 Nov 1828 by William Richarg (prob. a typo; Richard?) JP; voucher-not given; pg. 231 of Vol. 2 Belmont Co. Marriage Records.