You may want to check the spelling.
In Stephen F Austins Register of Families, are
___ Little, pg 1-69 (Vol i, pg 69)
Erastus & Harvey Litle, 2-97
John Litle, 1-45
John W Litle, 1-47
Wm Litle, 2-47
Wm L Litle, 1-36
Several women listed who may have been wives of above or widows.
Austins "Old 300" was the first group, arriving between 1821-1827. My Scotts, Standifers, Youngs' & Jones arrived in 1829, part of the "Little Colony", mostly settling in Ft Bend, Fayette & Bastrop Counties. In 1830, the Mexican Laws for Colonization changed to slow the influx, but Austin received permission to continue his efforts.
Texas GLO has several John & William Little's, some have been translated/transcribed. Kevin Kraus, at GLO will help you to get others translated, if needed. From the Land Grant Database, do not plug in a county. Just use the Surname in box for "Original Grantee" & you will see 761 results. (Counties: Austin, Angelina, Nacogdoches, Brazoria, Ft Bend, Montgomery, etc.) http://www.glo.texas.gov/cf/land-grant-search/LandGrantsWork...
Take a look at "Clerk Returns" for their witnesses. This can offer clues to family members, associations, future in-laws, etc.
Once you determine which John & William Little are your ancestors, you can use the GLO Map database to find early county maps, & maybe even original survey sketch. I just found a William Little of Ft Bend county map, 1839, map #3949. Property on Brazos River. Plug in only county name.http://www.glo.texas.gov/cf/ArcMaps/ArcMapsLookup.cfm
If they served in the Revolution, they also rec'd Bounty or Donation lands. Check Texas State Library & Archives Commission.https://www.tsl.state.tx.us/arc/genfirst.html
Herstein Library has lots of info. Verify Louis Kemps work, as errors have been discovered.
Check for probate records (wills, as well as minutes, for intestate circumstance) in the County where they settled, or subsequent land sales of the original league. Sometimes the labor was issued in a different location, so may be in different county.
Boundary lines changed frequently between 1836-1870, so check neighboring counties, too.
Here's another tibit for William Little, if this one is yours. From the Texas Historical Commission, Ft Bend Co. If toy call the historical commission, they should be able to tell you the co-ordinates from a map, if there is a marker, or if an Historical Marker may be ordered to be placed, etc.
From the link, select Ft Bend from drop down menu, then search. This will bring up all Historical monuments, cemeteries, homes, etc. go to page 13 for the item below & a link to the map.http://atlas.thc.state.tx.us/shell-county.htm
Cemetery Number: FB-C161
Primary Name: William Little Grave
County: Fort Bend
Date of Survey:
City: Missouri City
Directions to Cemetery: see notes
Rough Dimension (ft): 0
by Rough Dimension (ft): 0
Estimated Acres: 0
Approximate Number of Graves:
Dates of Burials:
Time Periods of Burials: na