Would your de los Santos and Sosa ancestors be from Tamaulipas, Mexico. I happen to have a 2nd great grandfather that was 1st married to a Sosa (also his first cousin) who had a son with his second wife (Chaves) who had a son named Juan Antonio de los Santos, for which my father was named.
If nothing else this proves to be an interesting coincidence. The above mentioned individuals lived in Mexico in the time period of 1825 to 1933. Write me, maybe we can find a common link.