Joohn Spindle came to Virginia from England before 1750. he owned land in Spottsylvania Co. Va. and what is now Lexington, Ky. He married Bridget Martin and had several children, one of whom was John E. Spindle woh moved to Hustle, Essex County, Virginia and married Mary Sears nee Barbee. They had Barbee (m Frances Gatewood, Rebecca Jones, and Ann "Nancy" R. Jones), Ann, Louis, Mordecai (m Sarah "Sally"), Phillip (m Fanny Noel).
Barbee had Elizabeth (m James H. Garnett), Joseph Clarence (m Sophia Frances Burke), Mordecai S.
Joseph Clarence had John Muse Burke (m Mary Lou Tabb),Barbee Burke (m Sue Talioferro), Betty G. (m Carter), Cordelia Fauntleroy (m Butler Edwards Pollard), Fanny Burke, Frank Woolfolk, Joseph Clarence, Julia Holms, Lewis, Margaret.