In answer to your question as to who Isaac Janney's wife was, She was Hannah Bishop, daughter of John Bishop and Mary (last name unknown). She was born in Chester Co., Pa. ca 1751 was said to have been married in Chester Co., PA however some say Bucks Co., Pa where Isaac was born. Hannah's parents were Samuel Bishop Sr. and Alice Curtis. Samuel Bishop Sr. was born in England in 1669 and came to America as a bonded servant when he was 13 years in 1682. He was bonded to James Sandeland on one of William Penn's ships and befire long he received his head right and became rather prominent in the community. Alice and Samuel Bishop Sr. had 13 children: Joseph; Rachel, Sarah. Hannah. Susannah, Alice, and Lydia, Mary, John, Priscilla, Charles, Rose and Samuel Bishop Jr.
Samuel Bishop Sr left a will dated 28 Nov 1741, proved on 14 Dec 1741. The first 4 of these children were baptized in the same year of 1704, 2 on Sep 10, and 2 on Dec 16. However, Rachel was not listed in his will, so she must have died young. Samuel Bishop Jr., was not listed in his will either because he died prior to his father, on Sep 16, 1741. Samuel Jr, also left a will naming his wife Hester/Esther Tranter and his unborn child and the rest of it to his brother John Bishop.
The Bishop;s were not Quakers, but Episcopalian however they did intermarry with them a good bit. John Bishop Sr., married Mary (whoever) probably sometime in the 1730's. They had 6 children that we can find. Mary; John; Nancy; Hannah, Sarah 'Sallie' Bishop and William Bishop. I am not sure when John and Mary and their family moved to Frederick Co., Va and Loudoun Co., Va, but they did ;live there for awhile. I believe some of them moved over into Berkley Co., WV. Isaac and Hannah moved on down to Franklin Co., Va, as did her brother John Bishop and his wife Elizabeth Babb, who was also a Quaker. Eventually, John moved first to Sullivan Co., Tenn. where he bought land. around 1799 or 1800, the Bishop's moved to Lee Co., VA, which became Scott Co., Va in 1813. I think I read where Isaac Janney died in 1805, which would leave Hannah able to remarry.
I think I also have some Janney's that are married into my Quaker Gregg line of New Castle Co., Delaware.
Hope this helps some. If you have any more questions re: the Bishop family, you can contact me at email@example.com
Betty Bishop Willoughby