My grandfather, Louis (Lev) Kisner (Kirzhner) and two brothers, Joseph and Nathan, immigrated from Shepetovka to Boston. Their parents were David Kirzhner (or something similar) and Mindl Mamzel. I just learned that my grandfather also had a brother Jacob, who died in childhood, and a sister Ethel (probably Etta or Ita) who was a dentist and whose three children moved to Israel. I'm trying to find information about other family in Russia. Louis had a nephew named Avram and niece Liza, presumably Ethel's children.

If any of this rings a bell or dates would be helpful, please let me know. Good luck with your research.