My paternal grandmother was Alice Emma Noe (nee Brenton). Crispin Brenton is her great granduncle. Crispin's brother Francis Brenton had a son Joel Brenton (1829-1906)who emigrated to Pittston, PA. Joel Brenton was a painting contractor in Pittston. His son, Frank Joel (1853-1921), was my grandmother's father.
The only thing I know about Crispin is his wife's name was Mary and she lived from 1803-6/30/1866. Crispin was born 7/13/1803 and died 8/1/1861 and he had 3 brothers (Francis, Samuel and James) and 3 sisters (Mary, Anis and Polly).
The Brentons from my family seem to stay in the PA area until 1940s. My only Brenton cousin now lives in Rochester, NY.
Hope that helps a little