Isaac Buffalo Jr. was my gggrandfather. I too am interested in finding if he had any Native American heritage. My grand mother, Rhoda Langston Wilkinson always told us that "You ain't got no Injun blood " but the family always figured we were part Cherokee. His father, Isaac Buffalo, Sr. was born in North Carolina in 1784 and died in Tennessee in 1845 according to records on Ancestry.com . His grandfather was
Henry Buffaloe (1740-1806) North Carolina and his ggrandfather
was Arthur Buffaloe (1710-1759) N.C. Arthur's father is just listed as Buffaloe.