Thanks for the info about Isham Cain.
Isham Cain, according to the US Census in 1850 for Coffee County, AL,was than 45 years old and his wife was Elizabeth A., aged 41, and they had children as follows:
James N. b 1829 in NC
Mary J. b 1835 in NC
John M. b 9 May 1836 in NC (my husband's g-g-grandfather)
Susannah H. b 1840 in NC
Thomas C. b 1843 in AL
Frances M. b 1845 in AL
Margaret E. b 1848 in AL
The family has lived in Coffee County, AL, almost exclusively until recent decades. Living near them in Coffee Conty, AL, in 1850 were several families of Meeks - John, Reddin and Lacey - all born in NC. Could Isham's wife's maiden name be Meeks? There have been numbers of Cain and Meeks marriages in AL.
Interestingly, John M. Cain named a son William Yancey Cain(my husband's grandfather)
and in the Library in Salt Lake City I discovered a William Yancey Cain in Mississippi of about the same age as our Wm Yancey. Do you know the Yancey connection?
Thanks for your help.
Martha Tootle Cain