I have a Samuel Juda von Flatow b. 1751-1780 and d. 1803-1843. So far I believe I've found 2 sons, Joseph b. 1802 d. 1867 (married to Henriette Berant ) and Bernard b. 1806 d. 1869. Joseph's children were:
Samuel 1832-1884
Marichen (married a Thorner) 1834-1917
Simon J. 1835-1909 marr. to Bertha Berant
Esther 1837-1876
Bernard 1839-1896
Adolph 1841-1909
Therese 1842-1897
Benno (probably Benjamin) 1844-1897
Julius 1846-1898
Max 1853-1891
I have all the descendants from Simon J and some from Bernard but all else is a mystery I would love to solve. All originated from Prussia/Germany. Thanks.