My gr-gr-grandfather, John GUINANE of Annagh townland, Murroe Parish, east Co Limerick had a sister Mary GUINANE, born July 1823 in Annagh. She married James DUGGAN on Jan 15, 1845, in Murroe Parish, and had 3 sons before emigrating to US: Stephen (1846), Martin (1848) & Timothy (1849). The family moved to Colorado, via St. Johns, Nebraska. They had a farm on the Platte River in Littleton, CO. Much has been written about Martin, who became the (in-)famous Marshal of Leadville, CO, during its heyday. The History of Leadville & Lake County by the Griswolds gives extensive detail.
Although not complete, I have quite a bit of info on this family. Children born in the US were Thomas, Kate, George & Maggie. Many are buried at Riverside Cemetery, Denver. Any more info welcome! Nancy Peregrine