Margaret Susan Keffer was born 12 May 1863 in Nicholas Co, WV. Her mother was Rachel Neff Keffer. We've never found a marriage.
Rachel had four children:
Abraham Keffer/Keiffer, b. abt 1860
Margaret Susan, b. 1863
Maria, b. abt 1864, m. MacArthur V.Corbitt
Samuel Austin Keffer/Keiffer, b. 6/4/1866
She is found in the 1870 census in the household of Isaac and Ruth Hughes in Grant Twp, Nicholas County.
We only know the four were siblings because there was a letter between two of them naming their sibs.
Abraham was raised in the household of Cynthia Higginbottom Keffer, wife of Henry who died after the 1860 census.
He is married by the time of the 1880 census, to Susan Donalson.
On the death record of Samuel Austin, his mother is listed as Rachel and father as Henry. This may be completely erroneous, but if it were true, it is still impossible to tell whether it is Henry (Sr) who married Cynthia in his old age, or Henry Jr, who was closer to the right age, but also a married man like his father.
There have been a number of researchers who have contributed bits and pieces to put this scenario together. None of us can determine who Margaret's father was, but it is pretty clear they are all related to Henry Keffer of Nicholas County, who was born abt 1800 in Giles Co, Virginia, to Jacob Keffer and Margaret (Peggy) Fizer.