These are the spellings that I have found so far - hopefully may there be a connection.
MYSKOFSKI, Joseph m. Mildred Witkofska before 1887 somewhere.
MYSKOFSKI, John married twice. 1st wife Helen (last name unknown) They had son Joseph MYSZKOWSKI born 1916.
2nd wife Anna Malik m. 1925 They had 2 daughters spelling MIECZKOWSKI.