Some trees have Enoch O'Brien born in 1779 and married to Nancy Barker in VA, and then married to Naomi Nancy Parker in Ohio - and dying in 1837 in Hancock, IN. I don't think the Enoch born in 1779 is the same one that married Parker.
Enoch O'Brien and Naomi Nancy Parker (she went by either Naomi or Nancy and many of her grandchildren were named one or the other) were definitely married in Brown, OH, in 1821 (the image is on my tree). The 1830 Brown, OH, Census shows Enoch O'Brien: 1 male Under 5 (George Washington O'Brien); 1 male 5-9 (Stephen Parker O'Brien); 1 male 20-29 (Enoch); 1 female Under 5 (Naomi Nancy O'Brien); and 1 female 20-29 (Naomi Nancy Parker O'Brien). Then Enoch buys land in Hancock, IN, in 1831, and dies there in 1837.
There are a whole lotta Enoch O'Brien's out there! I think the born-1779 one is probably related to Enoch's father George (born 1772, in VA), maybe his brother.