Briefly....In SC there are two Beeks lines, one white and one black. The black line are from the slaves the Beeks owned.
The white Beeks originated out of Bucks Co, PA with the spelling of Beakes and that name is still found in PA, NY and NJ. The clan that moved from PA to SC, the spelling got changed during census taking and doing legal paperwork. The white Beeks didn't own slaves in PA but when the moved and originally settled in Newberry Co, SC they then had slaves. In 1849, one of the sons' and his family moved with some slaves to MS and settled in the Aberdeen area. Some of the clan and descendants of the slaves still live there today, as in Greenville Co, SC and the surrounding areas.
The Beakes are of English descendent rather than German as you mentioned.
Runaway slaves did live with the Indians, so there could be Indian blood in your line but of course you need to trace your line and do DNA testing.
If I can be of any help, let me know.
Dawn Beeks firstname.lastname@example.org