There are at least two groups of Waddles in Ross, OH who may or may not be close cousins. Francis and family came from Ireland. Samuel and family came from Kentucky, possibly the Fleming / Mason County area:
1794, May 07: ELEANOR BEARD, m. SAMUEL WADDELL, Fleming County, Kentucky.
Name: Samuel Waddle
TAX RECORDS; 1800 Tax records of Fleming county, KY sec A
1 male over 21; 2 horses
50 A. Fleming creek
First Session Buckskin Presbyterian Church So. Salem,Ross Co, Ohio pg. 50
Anno Domini 1805
The following presons, members of Concord Church, were received to Communion at that time by examination: Philip Gossard, Mary Gossard, Casper Plyley, Perry Plyley, Caty Gossard, Charles Briggs, William Blair, Henry Snyder, Sam'l Waddle, Nelly Waddle, Mary Waddle. Polly Gossard could not see her way clear tho she had met the approbation of the Session.http://www.ohiogenealogyexpress.com/fayette/fayetteco_pionee...
Wm. McVery, a farmer. Francis Waddle, farmer and large grazer. William Waddle, farmer, and class-leader in the M. E. Church.
Waddel, Matthew Freshour, Hetty 1819 May 20
Waddle, Francis (Ireland) Baird, Jane 1806 Oct. 14
Waddle, James Freshour, Ann 1823 Mar. 25
Waddle, John Blair, Polly 1807 Jan. 20
Waddle, John Mann, Nancy 1806 Nov. 18
Waddle, Samuel (Kentucky) McClean, Eliz 1808 Jun. 17
Waddle, William Breaden, Sarah 1829 Sep. 24
Waddle, William McCoy, Jane Sarah 1845 Jun. 19
Beard, Sarah Robertson, Alexander 1834 Aug. 30
Wadde; Margaret Taylor, James 1845 Feb.20
Waddle, Elizabeth Colwell, Robert 1844 Aug. 22
Waddle, Isabel Blair, James 1810 Sep. 28
Waddle, Mary Pilley, John 1820 Jan. 27
History of Fayette County : together with historic notes on the Northwest, and the State of Ohio, gleaned from early authors, old maps and manuscripts, private and official correspondence
778 HISTORY OF FAYETTE COUNTY.
Henry Snider was a native of Virginia, and inmiigrated to this
county, from that state, in 1810, settling on land which he pur-
chased of Samuel Waddle.
SAMUEL WADDLE, Judge Daniel McLean's step-father, was a Kentuckian by birth ; removing to Ross County, Ohio, from whence he came to Fayette, in March, 1810, locating on a piece of ground four or five miles south of Washington. During the Indian troubles of 1812, he engaged in the defense of his country, being chosen major. In 1814 he removed to Washington and two years later engaged in the mercantile business, continuing in the same till his death, which occurred in 1828. In 1814 he purchased seven lots in the town of Washington, for which he paid in cash $10,000. After his death the property did not realize $1,000 outside of the dower set aside for his widow. This instance is cited to illustrate the terrible depreciation of property during that period.
(Source: History of Fayette Co.., Ohio - Dayton, Ohio: Odell & Mayer, 1881)