In our Mitchell family history we have: Elizabeth Mitchell (b 1765 d 1846) married Samuel McCullough who died in June 1800 near Big Darby Creek, Union County, Ohio. Elizabeth and Samuel had two children, Alexander (b abt 1798 d 1877) and Samuel (b 1800 d 1871). Elizabeth remarried, John Taylor (b 1771 d 1849) with whom she had two children, John and Margaret.
According to the 1883 Union County History, Samuel McCullough was the first white man to die in Union County, Ohio.
Is this helpful? Cheers. Regena