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DNA Testing French Canadian Native American ancestry

DNA Testing French Canadian Native American ancestry

Posted: 16 Aug 2011 12:55AM GMT
Classification: Query
My mother's father's family were originally from France, but migrated
to Quebec in the early 1600's and remained there for 300 years.
It is thought that there was some intermarriage through the centuries
with native Americans.

I would like to obtain DNA testing to determine the percentage of
native american ancestry and possibly identify specific tribal groups.
This is for my own use and education.

Can any one recommended specific tests and companies?
The family tree and DNA tribes testing look like candidates.
Thank you for your help.

Julie (St. Aubin)

Re: DNA Testing French Canadian Native American ancestry

Posted: 17 Aug 2011 2:43PM GMT
Classification: Query
I would definitely go with the Family Finder test at Family Tree DNA (FTDNA) in your situation. Not only will it tell you the percentage of various ancestries, but you'll also receive genetic matches with other people who are related. There are already a few people on FTDNA's forum with French-Canadian ancestry, and many more who've tested.

Unfortunately, the resolution down to tribal level isn't very good at any of the companies yet. For political reasons, Native American tribes are being advised against genetic testing. As a result, the only reference populations available are from Greenland, Mexico, and Central and South America.

As an additional incentive when testing with FTDNA (or 23andMe, but genealogy plays second fiddle there) is the opportunity to download your raw data and use it with many third-party utilities.

Re: DNA Testing French Canadian Native American ancestry

Posted: 17 Aug 2011 10:12PM GMT
Classification: Query
Many thanks Nathan for your informative and helpful reply.

What are some of the possible third part utilities for the
raw data?

Julie

Re: DNA Testing French Canadian Native American ancestry

Posted: 17 Aug 2011 10:35PM GMT
Classification: Query
This post was deleted by a board administrator on 18 Aug 2011 12:56PM GMT

Re: DNA Testing French Canadian Native American ancestry

Posted: 18 Aug 2011 2:33AM GMT
Classification: Query
Nathan:

Again thank you for your informative reply.
I had no idea there were so many uses of the DNA raw data.
It is a bit overwhelming.

But I am strongly leaning towards the FTDNA, and then following
the third party utility route to fine tune the data.

Thank you Nathan!

Julie

Re: DNA Testing French Canadian Native American ancestry

Posted: 18 Aug 2011 5:46PM GMT
Classification: Query
[Re-posting because moderator mistakenly assumed it contained a commercial link; it doesn't.]

The most useful I've found is GEDmatch (http://gedmatch.com/), which can compare DNA cross-company, i.e. FTDNA and 23andMe. It also has tools for comparing GEDCOM files and triangulating your matches, which might help figure out how you're related.

Then there are a variety of projects by both academics and hobbyists to determine the ethnicity of your ancestors more finely-grained than any company currently offers. One academic one, and relative newcomer, is Interpretome from Stanford University (http://esquilax.stanford.edu/). The most extensive one is called the Dodecad Ancestry Project (http://dodecad.blogspot.com/), which normally requires four grandparents from the same Eurasian ethnic group. However, he's recently released tools you can use to do the same analysis yourself.

If you are interested in the health aspects of your DNA, you can use Promethease (http://snpedia.com/index.php/Promethease) to explore that.

That's only scratching the surface of tools available now, and it's an active area of research and development. Here's a whole list of third party tools (http://www.23andyou.com/3rdparty), which although intended for 23andMe customers, work just as well for data from FTDNA.

[Note to moderators: The last link is NOT a commercial entity. The name of the website, 23andYou, is a play on words about the commercial entity, 23andMe–notice the difference? Please verify your assumptions about links before removing posts, simply by visiting the link in question. The bottom of every page on that website clearly states "Not affiliated with 23andMe." The About page (http://www.23andyou.com/about), makes it even more explicit it isn't a commercial entity:
"This site is not affiliated with 23andMe.com in any way.

This site was put together by a 23andMe member for the benefit of other 23andMe members. This information on this site was culled from several sources, predominantly from posts on the 23andMe Community Forums. Many thanks go to those who contribute to those forums."]

Re: DNA Testing French Canadian Native American ancestry - Promethease Question

Posted: 17 Aug 2013 11:55AM GMT
Classification: Query
Edited: 17 Aug 2013 2:30PM GMT
Nathan,

I see you have experience with Promethease. Perhaps you could give me some guidance.

I recently received my Autosomal DNA results and ran the raw data through Promethease. The reports showing research directly related to my SNP for health condition and medicine are impressive. However, when I cross-checked the RS numbers in the Promothease report with my raw DNA data, none of the numbers matched.

Any idea how I should interpret that?

Re: DNA Testing French Canadian Native American ancestry - Promethease Question

Posted: 17 Aug 2013 9:57PM GMT
Classification: Query
Edited: 18 Aug 2013 2:10PM GMT
> However, when I cross-checked the RS numbers in the Promothease report with my raw DNA data, none of the numbers matched.

> Any idea how I should interpret that?

If the rs#s didn't match, promethease wouldn't have told you about them.

If the genotypes for a particular rs# didn't match, you were perhaps seeing snps from the minus strand, which were being affected by
http://snpedia.com/index.php/Orientation

Can you provide a specific example to clarify what didn't match?

Re: DNA Testing French Canadian Native American ancestry - Promethease Question

Posted: 18 Aug 2013 3:34PM GMT
Classification: Query
Well, as is often the case when I pulled together the specific example I found my problem. The filter function in my excel version of the raw DNA data was not set up correctly, so I was not finding the flagged rs numbers. I find them all now.

Thank you for your reply!

Re: DNA Testing French Canadian Native American ancestry

Posted: 23 Aug 2013 9:00AM GMT
Classification: Query
Per Doug McDonald, 23andMe is the best of the 3 for biogeographical analysis. Many people used to send their data to him, but he said that 23andMe's Ancestry Composition is as good as his.

http://www.isogg.org/wiki/McDonald%27s_BGA_project
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