The place where your ancestor comes from is probably Irvinestown. Looking at the 1901 census for that area there were two Hetherington families farming there. One in Drumsara, parish of Derryvullan & the other in Glencoonra, parish of Magheracross. Perhaps these might be related to Noble?http://www.census.nationalarchives.ie/search/?then
There were Hetheringtons farming in both in Griffiths Valuation in 1862, so they seem to have been in that are a awhile. http://www.askaboutireland.ie/griffith-valuation/index.xml?a...
The families were both Church of Ireland. It might be worth checking the parish records to see if you can find a baptism or marriage for Noble.
Some of Derryvullan’s records start in 1803, and Magheracross’s in 1800. Copies are held in PRONI, Belfast.