I have the following information on Thomas Hughes and his wife Margaret Lougheed. It comes from the booklet "Robert Lougheed and Jane Henry" which was put together by Michael Cowan, Jopie Loughead and myself in 1991.
"Margaret Lougheed (6 October 1828 - 4 March 1891)
She married Thomas Hughes (29 May 1825 - 21 February 1888) son of Anthony Hughes on 2 October 1849. Margaret was his second wife. (Thomas was prviously married to Mary Murdoch, by whom he had a daughter Mary Jane Hughes, born 23 October 1847, died 1940. Mary Jane was married on 5 December 1867 to John Lougheed of Albion Township, Peel County, the son of James and Margaret Lougheed.
Thomas Hughes owned and farmed Lot 9, Concession 2 in Metcalfe Township of Middlesex County. In September of 1881, he and Margaret sold the west half of this lot to their son Anthony. Their son Thomas Samuel inherited the east half. Thomas Hughes was active in local politics and was elected to the Middlesex County Council as Reeve for several years. He and his wife are buried in Strathroy Cemetery, Strathroy, Ontario."
Their children are: Angelina married Lewis Arnett, Elizabeth Arabella married John Cuddy, Annie Maria married Joseph Henry Hughes, Anthony married Mary Victoria Cuddy, Robert Lougheed, Thomas Samuel married Matilda Morgan, Philo Henry married Harriett S. Taylor