My gg-uncle kept a log. He came from Hickman County, Tennessee to Carroll County, Arkansas in 1857. He crossed the Tennessee River ar William O. Britts place (a large general store and warehouse on the east bank of the Tennessee) and then up to Columbus Kentucky where he crossed the Mississippi and across southern Missouri.
A ferry began operations at Columbus in 1825 and ceased operations in 1981. Belmont Mo. was just across the river from Columbus.