Thanks for replying. I have restarted my laptop several times, even left it off for a day, but I double click the desktop icon, and also tried via the "Start, All Programs, etc" method and on my laptop the cursor starts to rotate for a few seconds ,then..... nothing happens.
I have been using FTM 2012 since 4th March with no problem, syncing OK with the tree on Ancestry.co.uk, successfully until about 2 days ago, and now nothing.
As far as I am aware nothing has changed/updated on my laptop over the last couple of days. Its really frustrating.